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Tylenol 8 Hour Acetaminophen 650 mg Extended Release Caplets, Fast Acting Bi-Layer Design, Quick & Long Lasting Pain Relief for Muscle, Joint, Back & Arthritis Aches, Fever Reducer, 100 Count

Original price was: $16.59.Current price is: $12.37.

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Price: $16.59 - $12.37
(as of Jul 27, 2025 21:04:41 UTC – Details)


Tylenol 8 Hour Muscle Aches & Pain Acetaminophen 650mg Extended Release Tablets are the #1 doctor recommended brand for pain relief and fever reduction, providing trusted over-the-counter medication for adults and children 12 years and older. Each bi-layer tablet contains 650 mg dose of acetaminophen, with a fast-acting layer for quick relief and an extended-release layer for up to 8 hours of relief. These pain relief pills are designed to be gentle on the stomach when taken as directed. Tylenol 8 Hour Muscle Aches & Pain is formulated to relieve a wide range of conditions, including minor muscle pain, joint pain, back pain relief, minor arthritis pain, headache, toothache, menstrual cramps, and minor aches and pains due to the common cold. The extended-release technology ensures long-lasting relief, reducing the need for frequent dosing and supporting uninterrupted daily activities. This product also temporarily reduces fever. The 100-count bottle offers a convenient supply for extended pain management, making it ideal for home, travel, or work. Key benefits include rapid onset of action, up to 8 hours of relief, and a formulation that is gentle on the stomach. Tylenol has a commitment to safety and efficacy, which means you can trust this acetaminophen 650mg extended release formula for effective, long-lasting relief from a variety of pain types. Choose Tylenol 8 Hour Muscle Aches & Pain for reliable, doctor-recommended pain relief pills that address muscle, joint, and minor pain of arthritis, as well as back pain relief products and headache medicine. Safe when used as directed.
Is Discontinued By Manufacturer ‏ : ‎ No
Product Dimensions ‏ : ‎ 2.38 x 2.38 x 4 inches; 3.97 ounces
Item model number ‏ : ‎ 493961
Date First Available ‏ : ‎ February 6, 2016
Manufacturer ‏ : ‎ Kenvue
ASIN ‏ : ‎ B01BGEVWBO
Best Sellers Rank: #2,670 in Health & Household (See Top 100 in Health & Household) #18 in Acetaminophen
Customer Reviews: 4.8 4.8 out of 5 stars 14,169 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });

Fast-acting & long-lasting relief: acetaminophen 650mg extended release bi-layer tablets deliver quick pain relief for muscle, joint, back, and arthritis aches; up to 8 hours of effective relief in each 100-count bottle
Bi-layer extended-release design: dual-layer tablets provide a fast-acting dose for rapid pain relief, then sustain effects for up to 8 hours; gentle on the stomach and ideal for minor arthritis, muscle, and joint pain
Pain relief pills for multiple uses: relieves minor muscle aches, joint pain, back pain, headache, toothache, menstrual cramps, and pain from the common cold; suitable for adults and children 12 years and older
Fever reducer & safety profile: 650 mg acetaminophen tablets temporarily reduce fever and alleviate minor aches; excellent safety profile when used as directed, gentle on the stomach
Trusted brand & doctor recommended: Tylenol is the #1 doctor recommended brand for pain relief and fever reduction; each 100-count bottle provides reliable, extended-release pain relief pills

Customers say

Customers find this extended-release Tylenol effective for muscle and joint pain, with one noting it works better than traditional 500 mg versions. The medication lasts up to 8 hours, is easy to swallow, and customers consider it better than Extra Strength. They appreciate its speed, with one mentioning it’s effective within a few minutes, and consider it a good value for the price. Customers like it as a sleep aid, helping them get through the day, and one notes it’s a good alternative to Aleve and Excedrin.

8 reviews for Tylenol 8 Hour Acetaminophen 650 mg Extended Release Caplets, Fast Acting Bi-Layer Design, Quick & Long Lasting Pain Relief for Muscle, Joint, Back & Arthritis Aches, Fever Reducer, 100 Count

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  1. Ms. T

    Amazing product I promise you you won’t be disappointed
    This product is amazing. Immediate relief with my muscles and joints are tight and aching. It totally relieves it. I lie down for about 10 minutes to let it start working amazing I cannot say enough about this product other than I will not stop taking it. I give it a 10 out of 10.

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  2. Jenn

    Love the Extra Strength
    Great and consistent product. I purchased to have on hand for surgery recovery and they got the job done. Easy to swallow and will purchase again

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  3. Barbara

    QUALITY AS DESCRIBED
    WORKSJUST ENOUGH TO EASE PAIN OR ACHES

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  4. lowell k lefers jr.

    Pain reliever
    Works great for muscle soreness

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  5. Jacqueline

    Really helpful product
    I have taken Tylenol for muscle aches for years as needed; to me, this is better than Extra Strength. It really helps relax my body.

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  6. Mon Saad

    Effective Extended Pain Relief
    Targets muscle/joint pain well. Bi-layer offers fast & long relief. 8-hour action is convenient. Gentle on stomach.

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  7. Carol H

    Worth it!
    Takes care of the pain! Great value!

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  8. Alma Ceballos

    Good pain reliever
    Work as recommended

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    Tylenol 8 Hour Acetaminophen 650 mg Extended Release Caplets, Fast Acting Bi-Layer Design, Quick & Long Lasting Pain Relief for Muscle, Joint, Back & Arthritis Aches, Fever Reducer, 100 Count
    Tylenol 8 Hour Acetaminophen 650 mg Extended Release Caplets, Fast Acting Bi-Layer Design, Quick & Long Lasting Pain Relief for Muscle, Joint, Back & Arthritis Aches, Fever Reducer, 100 Count

    Original price was: $16.59.Current price is: $12.37.

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