Cetaphil Deep Hydration Fragrance Free 48 Hour Activation Serum, 1 Fl oz, 48Hr Dry Skin Face Moisturizer for Sensitive Skin, With Hyaluronic Acid, Vitamin E & B5, Dermatologist Recommended
Original price was: $19.49.$18.47Current price is: $18.47.
Price: $19.49 - $18.47
(as of Aug 08, 2025 19:13:17 UTC – Details)
CETAPHIL DEEP HYDRATION 48 HOUR ACTIVATION SERUM instantly absorbs to deeply replenish skin’s hydration for 48 hours and improve the overall quality of sensitive skin. Features HydroSensitiv Complex which deepens dynamic hydration and soothes skin sensitivity. This lightweight serum also includes hyaluronic acid, sunflower seed oil, vitamin B5 and antioxidant rich vitamin E to rehydrate and restore skin’s appearance while soothing dry skin and dehydrated skin. Can be used alone or layered under face lotion or cream to provide a deep boost to skin’s hydration. Designed for sensitive skin, effective yet gentle skin care that won’t clog pores or irritate skin; fragrance-free & clinically tested on sensitive skin. DERMATOLOGIST RECOMMENDED for Sensitive Skin.
Product Dimensions : 1.68 x 1.56 x 5 inches; 2.14 ounces
Item model number : 0299.011700
UPC : 302990117004
Manufacturer : Galderma
ASIN : B0957ZBGBJ
Best Sellers Rank: #12,331 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #273 in Facial Serums
Customer Reviews: 4.6 4.6 out of 5 stars 1,175 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
CETAPHIL DEEP HYDRATION 48 HOUR ACTIVATION SERUM: Exclusive HYDROSENSITIVE complex deepens dynamic hydration and soothes skin sensitivity
DEEPLY REPLENISHES SKIN’S HYDRATION FOR 48 HOURS: Rehydrates skin to restore the appearance and improve the quality of sensitive skin over time
INSTANTLY ABSORBS AND IS LAYERABLE: lightweight serum can be used alone or layered under face lotion or cream to provide a deep boost to skin’s hydration
IDEAL FOR DRY AND DEHYDRATED SKIN: Formulated with hyaluronic acid, sunflower seed oil, vitamin B5 and antioxidant rich vitamin E to rehydrate and soothe
DESIGNED FOR SENSITIVE SKIN: Effective yet gentle skin care that won’t clog pores or irritate skin; features a gentle scent & clinically tested on sensitive skin
Customers say
Customers find the serum effective for sensitive skin, keeping it hydrated and moisturized, with one noting it soothes chapped skin overnight. They appreciate its creamy texture, non-greasy feel, and true lack of scent, while also considering it good value for money. Regarding skin reactions, while some customers report no breakouts or stinging, others mention their skin burning after use.
12 reviews for Cetaphil Deep Hydration Fragrance Free 48 Hour Activation Serum, 1 Fl oz, 48Hr Dry Skin Face Moisturizer for Sensitive Skin, With Hyaluronic Acid, Vitamin E & B5, Dermatologist Recommended
Add a review

Original price was: $19.49.$18.47Current price is: $18.47.
Vicki H –
Super hydrating!!!!!!
When I purchased this item, I’d been dealing with some health issues that left my skin in terrible shape (redness, dull appearance, rough texture, dry, etc). But let me tell you, the first time I used this product, it felt like the heavens opened up, the angels started singing and a light beamed down on me. ð¤£I tested it to see if my face would stay moisturized for 48 hours, and it didn’t disappoint. I cleansed my face with a gentle cleanser followed by a hydrating toner. Then I applied this serum. My face didn’t feel greasy. A little goes a long way. My face felt so soft and hydrated. And most of all, the redness and dullness had greatly diminished. It has a creamy texture and is fragrance free which I like because I have sensitive skin. But I have to get back to the hydration. My skin feels so plump and smooth and bouncy and shiny. I’ve been using it for about 6 months and it’s definitely a holy grail in my skin care routine. BTW, I’m a 55 year old African American who’s currently going through menopause (if that’s helpful to anyone). Trust me, if you try this product, you won’t be disappointed. And it’s very affordable.
Smileygen –
My skin is loving it
Gentle and moisturizing. Makes my skin feel so great , not greasy but definitely nourished .Highly recommendBuying it again for vacation
STEPHANIE A Thornton –
Donât let winter chap your cheeks!!
Winter is no match for this. Kept my face from chaffing and soft. Great value.
C. Gray –
Go to skincare
I love this lotion because it is lightweight and hydrating. There is no fragrance and it really helps with dryness. My husband even used it too. Great value compared to more expensive brands making it my go to skincare.
Melissa mangini –
Lotion
Like the consistency, smell and moisture it gives my skin
Jennie –
BUY IT
This product is amazing. It really does help with my alligator skin lol. I have dry skin and this saves the day. I wear over night and in the morning when I do my makeup it doesnât look dry, cakey , or flaked. Very hydrating, yet lightweight. It does have a light fresh scent. Easy on my sensitive skin.
Theresa Smith –
Great product!
Great for very sensitive, dry skin!
Leta H. –
BEST
GREAT. I love this product because it makes my face feel so good inside and out. Soaks in well and is non greasy. Great value, thick cream. It lasts all day. My skin looks and feels so much better after using this. Keeps my skin moist but not greasy.
ValentÃn Jerez –
Es más una formula cremosa, se absorbe rápido y me gustó mucho para preparar la piel antes del maquillaje. Mi piel es muy seca, con tendencia al eccema y sensible, si bien lo compré para el rostro me ayuda mucho para el eccema en mis manos, no se requiere mucho producto, tiene un olor extraño, pero se quita.
Ana Ma Flores Coulbourn –
Tengo rosácea y me salen espinillas quisticas y con este producto me han dejado de salir y me ha bajado la irritación.
Reyna Del Rosario Cigarroa Toledo –
Excelente producto para mà que tengo piel sensible me sirve mucho
Ziya Ul Islam –
Good for skin hydration.